Mesenchymal stem cells from umbilical cord tissue as potential therapeutics for cardiomyodegenerative diseases – a review

Hollweck, Trixi; Hagl, Christian; Eissner, Günther

International Journal of Molecular and Cellular Medicine (IJMCM)

Cellular and Molecular Biology Research Center, Babol University of Medical Sciences

Fri, May 9, 2025 [Archive]

Volume 1, Issue 3 (Int J Mol Cell Med 2012) Int J Mol Cell Med 2012, 1(3): 119-132 | Back to browse issues page

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Hollweck T, Hagl C, Eissner G. Mesenchymal stem cells from umbilical cord tissue as potential therapeutics for cardiomyodegenerative diseases – a review. Int J Mol Cell Med 2012; 1 (3) :119-132
URL: http://ijmcmed.org/article-1-45-en.html

Mesenchymal stem cells from umbilical cord tissue as potential therapeutics for cardiomyodegenerative diseases – a review

Trixi Hollweck¹

, Christian Hagl¹

, Günther Eissner²

1- Cardiac Surgery Department, Munich University Medical Center, Munich, Germany.
2- Cardiac Surgery Department, Munich University Medical Center, Munich, Germany. , Guenther.Eissner@med.uni-muenchen.de

Abstract: (13752 Views)

Heart failure is one of the leading causes of death worldwide. End stage disease often requires heart transplantation, which is hampered by donor organ shortage. Tissue engineering represents a promising alternative approach for cardiac repair. For the generation of artificial heart muscle tissue several cell types, scaffold materials and bioreactor designs are under investigation. In this review, the use of mesenchymal stem cells derived from human umbilical cord tissue (UCMSC) for cardiac tissue engineering will be discussed.

Keywords: Umbilical cord tissue, mesenchymal stem cells, cardiac differentiation, non-degradable scaffolds, polytetrafluorethylene, titanium, bioreactor

Full-Text [PDF 231 kb] (4700 Downloads)

Type of Study: Review | Subject: Hematology
Received: 2012/04/25 | Accepted: 2013/09/14 | Published: 2013/09/14