International Journal of Molecular and Cellular Medicine (IJMCM)
Babol University of Medical Sciences
Mon, Jun 9, 2025
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Volume 13, Issue 2 (Int J Mol Cell Med 2024)
Int J Mol Cell Med 2024, 13(2): 210-219 |
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Kakavandi E, Yavarian J, Farzanehpour M, Shayestehpour M. A Review of the Interaction between miRNAs and Ebola Virus. Int J Mol Cell Med 2024; 13 (2) :210-219
URL: http://ijmcmed.org/article-1-2314-en.html
URL: http://ijmcmed.org/article-1-2314-en.html
1- Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
2- Applied Virology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
3- Department of Bacteriology and Virology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. ,shayesteh2009@yahoo.co.uk
2- Applied Virology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
3- Department of Bacteriology and Virology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. ,
Abstract: (787 Views)
Ebola virus (EBOV) is a life-threatening and virulent pathogen that kills approximately 90 percent of infected individuals. Nowadays, microRNAs (miRNAs) have become a promising option for more efficient screening, diagnosis, monitoring, and therapy of numerous diseases such as cancer, stroke, Alzheimer's, and viral infections. Recent studies have revealed the role of EBOV and host-encoded miRNAs in Ebola virus disease (EVD), opening an avenue for developing novel drugs against EVD and diagnostic panels for EBOV infection. EBOV-encoded miRNAs such as miR-VP-3p and miR-1-5p and anti-EBOV host cell miRNAs such as has-miR-150-3p, has-miR-103b and has-miR-145-3p might be a possible diagnostic biomarker or druggable targets. This paper highlights the importance of viral and cellular miRNAs in EBOV infection and EVD.
Type of Study: Mini-review |
Subject:
Infectious disease (Molecular and Cellular aspects)
Received: 2024/04/3 | Accepted: 2024/08/11 | Published: 2024/08/12
Received: 2024/04/3 | Accepted: 2024/08/11 | Published: 2024/08/12
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