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Is Radiosensitivity Associated to Different Types of Blood Groups? (A cytogenetic study)
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Farideh Elahimanesh1   , Ali Shabestani Monfared 2, Meysam Khosravi Farsani1 , Haleh Akhavan Niaki1 , Zeinab Abedian1 , Karimollah Hajian-Tilaki1 , Sajad Borzouisileh1 , Nayer Seyfizadeh3 , Mehrangiz Amiri1 |
1- Cellular & Molecular Biology Research Center (CMBRC), Babol University of Medical Sciences, Babol, Iran.
2- Cellular & Molecular Biology Research Center (CMBRC), Babol University of Medical Sciences, Babol, Iran. , monfared_ali@yahoo.com
3- Department of Clinical Biochemistry, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran. |
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Abstract: (15499 Views) |
| Many biological factors affect radiosensitivity. In this study, radiosensitivity among the different blood groups was investigated. Peripheral blood sample of 95 healthy people were divided into two parts. One part was irradiated with 2 Gy Co-60 gamma rays and the second one was considered as control. Then all the samples were studied by cytokinesis-blocked micronucleus assay (CBMN assay). Our study showed that the radiosensitivity index of A+ and O+ groups was significantly higher and lower than other blood groups, respectively. It seems that blood type can be used as a radiosensitivity index for determining the given dose to radiotherapy, although extensive studies are necessary. |
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| Keywords: Radiosensitivity, blood group, CBMN assay |
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Full-Text [PDF 71 kb]
(6739 Downloads)
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Type of Study: Original Article |
Subject:
Cell Biology
Received: 2013/05/20 | Accepted: 2013/08/28 | Published: 2013/08/28
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