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Precision Medicine in Non Communicable Diseases
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Mandana Hasanzad1    , Negar Sarhangi2 , Hamid Reza Aghaei Meybodi2 , Shekoufeh Nikfar3 , Fatemeh Khatami4 , Bagher Larijani 5 |
1- Medical Genomics Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran; Personalized Medicine Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
2- Personalized Medicine Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
3- Personalized Medicine Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran; Department of Pharmacoeconomics and Pharmaceutical Administration, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
4- Chronic Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
5- Personalized Medicine Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. , larijanib1340@gmail.com |
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Abstract: (4694 Views) |
Non-communicable diseases (NCDs) are the leading cause of death and disease burden globally, cardiovascular diseases account for the major part of death related to NCDs followed by different types of cancer, chronic obstructive pulmonary disease, and diabetes. As the world health organization and the United Nations have announced a 25% reduction in mortality of NCDs by 2025, different communities need to adopt preventive strategies for achieving this goal. Personalized medicine approach as a predictive and preventive strategy aims for a better therapeutic goal to the patients in order to maximize benefits and reduce harms. The clinical benefits of this approach are already realized in cancer targeted therapy, and its impact on other conditions needs more studies in different societies. In this review, we essentially describe the concept of personalized (or precision) medicine in association with NCDs and the future of precision medicine in prediction, prevention, and personalized treatment. |
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| Keywords: Precision medicine, non-communicable diseases, cardiovascular diseases, type 2 diabetes, chronic obstructive pulmonary disease, cancer |
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Full-Text [PDF 665 kb]
(1702 Downloads)
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Type of Study: Review |
Subject:
Other
Received: 2020/04/10 | Accepted: 2019/08/20 | Published: 2019/08/28
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