دوره 5، شماره 2 - ( 1-1395 )                   | برگشت به فهرست نسخه ها


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Hosinian M, Qujeq D, Ahmadi Ahangar A. The Relation between GABA and L-Arginine Levels with some Stroke Risk Factors in Acute Ischemic Stroke Patients. Int J Mol Cell Med 2016; 5 (2) :100-105
URL: http://ijmcmed.org/article-1-452-fa.html
The Relation between GABA and L-Arginine Levels with some Stroke Risk Factors in Acute Ischemic Stroke Patients. مجله بین المللی سلولی و مولکولی. 1395; 5 (2) :100-105

URL: http://ijmcmed.org/article-1-452-fa.html


:   (9999 مشاهده)

Changes in extra and intracellular neurotransmitter amino acids concentration in the early stage of acute cerebral ischemia have been reported. In this the study, serum level of gamma aminobutyric acid (GABA) and L-Arginine in acute ischemic stroke patients was assessed. 60 patients with acute ischemic stroke and sixthy healthy volunteers as a control group were assessed. Serum GABA was measured with modified enzymatic method and serum L- Arginine was measured by modified Sakaguchi method. Serum GABA level in stroke cases was lower than that of the control group. There was no relationship between GABA level and age or gender. Also, no significant correlation was observed between GABA levels with ischemic stroke risk factors such as smoking, diabetes mellitus, and hypertension. Serum L- Arginine level in patients was slightly increased in comparison with control group. There was a positive relationship between serum L- Arginine level and acute ischemic stroke risk factors. Serum GABA level was reduced in patients and had no correlation with acute ischemic stroke risk factors.

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نوع مطالعه: Original Article | موضوع مقاله: Neurosciences
دریافت: 1394/10/21 | پذیرش: 1395/3/29 | انتشار: 1395/3/30

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