[صفحه اصلی ]   [Archive]  
:: صفحه اصلي :: درباره نشريه :: آخرين شماره :: تمام شماره‌ها :: جستجو :: ثبت نام :: ارسال مقاله :: تماس با ما ::
:: دوره 2، شماره 2 - ( 3-1392 ) ::
برگشت به فهرست نسخه ها
The role of microRNAs in cardiovascular disease
:   (13083 مشاهده)
Cardiovascular disease has become the main factor of death and birth defects in the world. There are some therapeutic structures and drugs for curative and palliative therapy of the disease, but to the aim of accessing reliable therapy or to postpone onset of disease, especially for individuals with heritable coronary artery disease in their pedigree Genetic engineering technologies are making advances in the field by identifying oligonucleotides with higher potencies which can be easily targeted against almost any gene, particularly interfering RNA (RNAi). Recently, the focus of RNAi approaches has encompassed the use of synthetic sequences to mimic or silence endogenous microRNAs (miRNAs) that are abruptly dysregulated following cardiovascular diseases. In this review, we summarize the role of miRNAs in heart development and vascular system as two main factors of birth defects and adult morbidity and mortality and miRNAS as new therapeutic agents.
متن کامل [PDF 67 kb]   (3201 دریافت)    
نوع مطالعه: Review | موضوع مقاله: Genetics & Disease
دریافت: 1391/12/20 | پذیرش: 1392/4/12 | انتشار: 1392/4/12
ارسال نظر درباره این مقاله
نام کاربری یا پست الکترونیک شما:

CAPTCHA


XML   English Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Ghaderian S M H, Aghabozorg afjeh S S. The role of microRNAs in cardiovascular disease. Int J Mol Cell Med. 2013; 2 (2) :50-57
URL: http://ijmcmed.org/article-1-76-fa.html

The role of microRNAs in cardiovascular disease. مجله بین المللی سلولی و مولکولی. 1392; 2 (2) :50-57

URL: http://ijmcmed.org/article-1-76-fa.html



دوره 2، شماره 2 - ( 3-1392 ) برگشت به فهرست نسخه ها
International Journal of Molecular and Cellular Medicine (IJMCM) International Journal of Molecular and Cellular Medicine (IJMCM)
Persian site map - English site map - Created in 0.04 seconds with 30 queries by YEKTAWEB 4219