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Cellular response to ionizing radiation: A microRNA story
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MicroRNAs (miRNAs) represent a class of small non-coding RNA molecules that regulate gene expression at the post-transcriptional level. They play a crucial role in diverse cellular pathways. Ionizing radiation (IR) is one of the most important treatment protocols for patients that suffer from cancer and affects directly or indirectly cellular integration. Recently it has been discovered that microRNA-mediated gene regulation interferes with radio-related pathways in ionizing radiation. Here, we review the recent discoveries about miRNAs in cellular response to IR. Thoroughly understanding the mechanism of miRNAs in radiation response, it will be possible to design new strategies for improving radiotherapy efficiency and ultimately cancer treatment.
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نوع مطالعه: Review | موضوع مقاله: Biomarkers (diagnosis & treatment)
دریافت: 1391/11/23 | پذیرش: 1392/4/12 | انتشار: 1392/4/12
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Halimi M, Asghari M, Sariri R, Moslemi D, Parsian H. Cellular response to ionizing radiation: A microRNA story. Int J Mol Cell Med. 2012; 1 (4) :178-184
URL: http://ijmcmed.org/article-1-67-fa.html

Cellular response to ionizing radiation: A microRNA story. مجله بین المللی سلولی و مولکولی. 1391; 1 (4) :178-184

URL: http://ijmcmed.org/article-1-67-fa.html



دوره 1، شماره 4 - ( 9-1391 ) برگشت به فهرست نسخه ها
International Journal of Molecular and Cellular Medicine (IJMCM) International Journal of Molecular and Cellular Medicine (IJMCM)
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