دوره 10، شماره 3 - ( 6-1400 )                   | برگشت به فهرست نسخه ها

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Yarahmadi A, Azarpira N, Mostafavi-Pour Z. Role of mTOR Complex 1 Signaling Pathway in the Pathogenesis of Diabetes Complications; A Mini Review. Int J Mol Cell Med 2021; 10 (3) :181-188
URL: http://ijmcmed.org/article-1-1707-fa.html
Role of mTOR Complex 1 Signaling Pathway in the Pathogenesis of Diabetes Complications; A Mini Review. مجله بین المللی سلولی و مولکولی. 1400; 10 (3) :181-188

URL: http://ijmcmed.org/article-1-1707-fa.html

Role of mTOR Complex 1 Signaling Pathway in the Pathogenesis of Diabetes Complications; A Mini Review
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The mammalian target of rapamycin (mTOR) is an evolutionarily conserved serine/threonine-protein kinase that senses and combines various environmental signals to regulate the growth and homeostasis of human cells. This signaling pathway synchronizes many critical cellular processes and is involved in an increasing number of pathological conditions such as diabetes, cancer, obesity, and metabolic syndrome. Here, we review different complications of diabetes that are associated with mTOR complex 1 imbalance. We further discuss pharmacological approaches to treat diabetes complications linked to mTOR deregulation.
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نوع مطالعه: Mini-review | موضوع مقاله: Clinical Biochemistry
دریافت: 1400/5/2 | پذیرش: 1400/8/24 | انتشار: 1400/10/20
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