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Central effects of camphor on GnRH and sexual hormones in male rat
:   (13459 مشاهده)
In Persian traditional medicine is believed that camphor (a crystalline ketone obtained from cinnamomum camphora) is a suppressor of sexual behaviors. This study examined the central effects of camphor on sexual hormones (LH, FSH and testosterone) and GnRH plasma levels in male rat. Male Wistar rats weighing 250-260gr were selected and divided into control (no treatment), sham (ICV injection of EtOH 10%) and treatment (ICV injection of camphor in three doses 4, 20, 40 µg/ 10µl in alcohol) groups. The serum samples were used for assaying of GnRH, LH, FSH and testosterone. There were no significant differences in the levels of hormones between the groups of study. Despite the central administration of camphor in hypothalamus - pituitary - gonad (HPG) axis, no significant differences were seen in sex hormone`s levels compared to the control. With this finding, it can be concluded that camphor may not effectively handle the axis via central pathway. These data recommend further studies of camphor on the HPG axis.
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نوع مطالعه: Original Article | موضوع مقاله: Clinical Biochemistry
دریافت: 1391/11/30 | پذیرش: 1392/2/21 | انتشار: 1392/2/21
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shahabi S, Jorsaraei S G A, Moghadamnia A A, Zabihi E, Aghajanpour Mir S M, Mousavi Kani S N, et al . Central effects of camphor on GnRH and sexual hormones in male rat. Int J Mol Cell Med. 2012; 1 (4) :191-196
URL: http://ijmcmed.org/article-1-71-fa.html

Central effects of camphor on GnRH and sexual hormones in male rat. مجله بین المللی سلولی و مولکولی. 1391; 1 (4) :191-196

URL: http://ijmcmed.org/article-1-71-fa.html



دوره 1، شماره 4 - ( 9-1391 ) برگشت به فهرست نسخه ها
International Journal of Molecular and Cellular Medicine (IJMCM) International Journal of Molecular and Cellular Medicine (IJMCM)
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