[صفحه اصلی ]   [Archive]  
:: صفحه اصلي :: درباره نشريه :: آخرين شماره :: تمام شماره‌ها :: جستجو :: ثبت نام :: ارسال مقاله :: تماس با ما ::
:: دوره 4، شماره 1 - ( 10-1393 ) ::
برگشت به فهرست نسخه ها
Rab11 in Disease Progression
:   (6399 مشاهده)
Membrane/ protein trafficking in the secretory/ biosynthetic and endocytic pathways is mediated by vesicles. Vesicle trafficking in eukaryotes is regulated by a class of small monomeric GTPases the Rab protein family. Rab proteins represent the largest branch of the Ras superfamily GTPases, and have been concerned in a variety of intracellular vesicle trafficking and different intracellular signalling pathways. Rab11 (a subfamily of the Ypt/ Rab gene family), an evolutionarily conserved ubiquitously expressed subfamily of Rab GTPases, has been implicated in regulating vesicular trafficking through the recycling of endosomes. Rabs have been grouped into different subfamilies based on the distinct unambiguous sequence motifs. Three members: Rab11a, Rab11b and Rab25 make up the Rab11 GTPase subfamily. In this review article, we describe an overview over Rab11 subfamily with a brief structural aspect and its roles in implicating different disease progression.
متن کامل [PDF 67 kb]   (1623 دریافت)    
نوع مطالعه: Review | موضوع مقاله: Genetics & Disease
دریافت: ۱۳۹۳/۶/۱۹ | پذیرش: ۱۳۹۳/۹/۳ | انتشار: ۱۳۹۳/۹/۲۵
ارسال نظر درباره این مقاله
نام کاربری یا پست الکترونیک شما:

CAPTCHA


XML   English Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Bhuin T, Roy J K. Rab11 in Disease Progression. Int J Mol Cell Med. 2015; 4 (1) :1-8
URL: http://ijmcmed.org/article-1-227-fa.html

Rab11 in Disease Progression. مجله بین المللی سلولی و مولکولی. 1393; 4 (1) :1-8

URL: http://ijmcmed.org/article-1-227-fa.html



دوره 4، شماره 1 - ( 10-1393 ) برگشت به فهرست نسخه ها
International Journal of Molecular and Cellular Medicine (IJMCM) International Journal of Molecular and Cellular Medicine (IJMCM)
Persian site map - English site map - Created in 0.06 seconds with 32 queries by YEKTAWEB 4071