[صفحه اصلی ]   [Archive]  
:: صفحه اصلي :: درباره نشريه :: آخرين شماره :: تمام شماره‌ها :: جستجو :: ثبت نام :: ارسال مقاله :: تماس با ما ::
:: دوره 8، شماره 1 - ( 2-1398 ) ::
برگشت به فهرست نسخه ها
Thymolipoma-associated Myasthenia Gravis with High Titer of Anti-MuSKAb: A Case Report
:   (260 مشاهده)
Myasthenia Gravis (MG) is a neuromuscular junction disorder caused by pathogenic autoantibodies to some parts of the post-synaptic muscle endplates. About 85% of generalized MG patients have autoantibodies against post-synaptic acetyl-choline receptors (AChR). From the 10-15% of the remaining patients, 45-50% are positive for Muscle Specific Tyrosine Kinase-Antibody (MuSK-Ab). It is believed that the thymus has a critical role in the pathogenesis of the disease with AChR-Ab, especially in patients with thymic abnormalities. In contrast, the role of thymus gland in MG with anti-MuSK-Ab is not clearly obvious. Patients with this antibody virtually have normal or only minimal follicular hyperplastic thymus. The presence of anti-MuSK Ab in a thymolipomatous (an uncommon tumor of thymus) MG is an atypical and new finding of MG because of not only thymolipoma but also presence of anti-MuSK antibodies which makes this case different from the previous reports of the antibodies-associated MG.  Here, we present a young woman with thymolipoma and MG (a very uncommon kind of tumor-associated MG) and high level of anti-MuSK-Ab.
متن کامل [PDF 359 kb]   (30 دریافت)    
نوع مطالعه: Case Report | موضوع مقاله: Biomarkers (diagnosis & treatment)
دریافت: ۱۳۹۷/۱۲/۱۴ | پذیرش: ۱۳۹۸/۳/۲۵
ارسال نظر درباره این مقاله
نام کاربری یا پست الکترونیک شما:

CAPTCHA


XML   English Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Poursadeghfard M, Abolhasani Foroughi A, Karamimagham S. Thymolipoma-associated Myasthenia Gravis with High Titer of Anti-MuSKAb: A Case Report. Int J Mol Cell Med. 2019; 8 (1)
URL: http://ijmcmed.org/article-1-1034-fa.html

Thymolipoma-associated Myasthenia Gravis with High Titer of Anti-MuSKAb: A Case Report. مجله بین المللی سلولی و مولکولی. 1398; 8 (1)

URL: http://ijmcmed.org/article-1-1034-fa.html



دوره 8، شماره 1 - ( 2-1398 ) برگشت به فهرست نسخه ها
International Journal of Molecular and Cellular Medicine (IJMCM) International Journal of Molecular and Cellular Medicine (IJMCM)
Persian site map - English site map - Created in 0.06 seconds with 32 queries by YEKTAWEB 3977