International Journal of Molecular and Cellular Medicine
مجله بین المللی سلولی و مولکولی
Int J Mol Cell Med
Medical Sciences
http://ijmcmed.org
1
admin
2251-9637
2251-9645
10.22088/IJMCM.BUMS
en
jalali
1392
6
1
gregorian
2013
9
1
2
4
online
1
fulltext
en
Antioxidant Activity and Glucose Diffusion Relationship of Traditional Medicinal Antihyperglycemic Plant Extracts
Clinical Biochemistry
Clinical Biochemistry
Original Article
Original Article
Plants with hypoglycemic properties are important in the treatment of diabetes. One of the mechanisms in reducing blood glucose is preventing the digestive absorption of glucose. The aim of this study was to evaluate the antioxidant properties of some traditional medicinal plants collected from different regions of Iran and their effects on glucose diffusion decrease. The amounts of phenolic compounds, total flavonoids, total polysaccharides, antioxidant activity and lipid peroxidation were determined respectively by folin ciocalteu, querceting, sulfuric acid, FRAP and thiobarbituric acid - reactive substanses (TBARS) in eleven confirmed traditional antihyperglycemic medicinal plants prepared at 50g/l concentrations using the boiling method. Phenolic compounds of Eucalyptus globules (100.8± 0.01 mg /g), total flavonoids content of Juglans regia (16.9± 0.01 mg /g) and total polysaccharide amount of Allium satirum (0.28± 0.05) were the highest. Significant relationship was observed between the polyphenols and flavonoids (p <0.05). The grape seed extract showed the highest antioxidant activity (133± 0.02 mg/g) together with decreased glucose diffusion as well as increased polyphenols (p <0.05), but the increase in antioxidant activity was not related to glucose diffusion. Antihyperglycemic plant extracts containing higher polyphenols showed more efficient in vitro glucose diffusion decrease, but no significant relationship was observed between antioxidant activity increase and glucose diffusion.
Antihyperglycemic plants, glucose diffusion, antioxidant activity, polyphenols, flavonoids
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176
http://ijmcmed.org/browse.php?a_code=A-10-110-1&slc_lang=en&sid=1
Fariba
Asgharpour
f_asgharpour@yahoo.com
10031947532846003568
10031947532846003568
No
Paramedical Faculty, Babol University of Medical Scienes, Babol, Iran.
Mehdi
pouramir
pouramir@yahoo.com
10031947532846003569
10031947532846003569
Yes
Cellular and Molecular Biology Research Center (CMBRC), Babol University of Medical Scienes, Babol, Iran.
Asieh
Khalilpour
khalilpour_62@yahoo.com
10031947532846003570
10031947532846003570
No
Paramedical Faculty, Babol University of Medical Scienes, Babol, Iran.
Sobgol
Asgharpour Alamdari
f_asgharpour@yahoo.com
10031947532846003571
10031947532846003571
No
Bureau of Education, Rasht-Region 2, Rasht, Iran.
Mehrasa
Rezaie
f_asgharpour@yahoo.com
10031947532846003572
10031947532846003572
No
Faculty of Veterinary Medicine University of Urmia, Urmia, Iran.