en Infectious disease (Molecular and Cellular aspects) Infectious disease (Molecular and Cellular aspects) Mini-review Mini-review <span style="font-family:Tahoma;"><span style="font-size:12px;"><span style="unicode-bidi:embed"><span style="line-height:107%">Ebola virus (EBOV) is a life-threatening and virulent pathogen that kills approximately 90 percent of infected individuals. Nowadays, microRNAs (miRNAs) have become a promising option for more efficient screening, diagnosis, monitoring, and therapy of numerous diseases such as cancer, stroke, Alzheimer&#39;s, and viral infections. Recent studies have revealed the role of EBOV and host-encoded miRNAs in Ebola virus disease (EVD), opening an avenue for developing novel drugs against EVD and diagnostic panels for EBOV infection. EBOV-encoded miRNAs such as miR-VP-3p and miR-1-5p and anti-EBOV host cell miRNAs such as has-miR-150-3p, has-miR-103b and has-miR-145-3p might be a possible diagnostic biomarker or druggable targets. This paper highlights the importance of viral and cellular miRNAs in EBOV infection and EVD<span dir="RTL" lang="FA">.</span></span></span></span></span> Ebola virus, MicroRNAs, virus diseases 210 219 http://ijmcmed.org/browse.php?a_code=A-10-3877-2&slc_lang=en&sid=1 Ehsan Kakavandi kakavandi55@gmail.com 100319475328460030485 100319475328460030485 No Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Jila Yavarian yavarian31@yahoo.com 100319475328460030486 100319475328460030486 No Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Mahdieh Farzanehpour farzanehpour22@yahoo.com 100319475328460030487 100319475328460030487 No Applied Virology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran. Mohammad Shayestehpour shayesteh2009@yahoo.co.uk 100319475328460030488 100319475328460030488 Yes Department of Bacteriology and Virology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.