TY - JOUR T1 - Cellular response to ionizing radiation: A microRNA story TT - JF - ijmcmed JO - ijmcmed VL - 1 IS - 4 UR - http://ijmcmed.org/article-1-67-en.html Y1 - 2012 SP - 178 EP - 184 KW - Cellular response KW - ionizing radiation KW - microRNA N2 - MicroRNAs (miRNAs) represent a class of small non-coding RNA molecules that regulate gene expression at the post-transcriptional level. They play a crucial role in diverse cellular pathways. Ionizing radiation (IR) is one of the most important treatment protocols for patients that suffer from cancer and affects directly or indirectly cellular integration. Recently it has been discovered that microRNA-mediated gene regulation interferes with radio-related pathways in ionizing radiation. Here, we review the recent discoveries about miRNAs in cellular response to IR. Thoroughly understanding the mechanism of miRNAs in radiation response, it will be possible to design new strategies for improving radiotherapy efficiency and ultimately cancer treatment. M3 ER -