%0 Journal Article %A Zarifian, Ahmadreza %A Farhoodi, Zeinab %A Amel, Roya %A Mirzaee, Salmahe %A Hassanzadeh-Nazarabad, Mohammad %T Balanced Chromosomal Rearrangement in Recurrent Spontaneous Abortions: A Case Report %J International Journal of Molecular and Cellular Medicine %V 1 %N 4 %U http://ijmcmed.org/article-1-54-en.html %R %D 2012 %K Chromosomal abnormality, Spontaneous abortion, Chromosomal translocation, Recurrent miscarriage, Case report, %X One of the major causes of spontaneous abortion before the fourth month of pregnancy is chromosomal abnormalities. We report an unusual case of a familial balanced chromosomal translocation in a consanguineous couple who experienced 4 spontaneous abortions. Chromosomal studies were performed on the basis of G-banding technique at high resolution and revealed 46, XX, t (16 6) (p12 q26) and 46, XY, t (16 6) (p12 q26) in both partners, which induced such pregnancy complications. Chromosomal balanced translocation is one of the most common causes of recurrent spontaneous abortions (RSA). In such cases prenatal diagnosis (PND) during the 16th week of gestation is strongly recommended. %> http://ijmcmed.org/article-1-54-en.pdf %P 225-228 %& 225 %! A case of recurrent spontaneous abortions %9 Case Report %L A-10-62-3 %+ Department of Medical Genetics, Faculty of Medicine, Mashhad University of Medical Sciences, Iran. %G eng %@ 2251-9637 %[ 2012