RT - Journal Article T1 - Metabolomics Analysis of Mesenchymal Stem Cells JF - ijmcmed YR - 2019 JO - ijmcmed VO - 8 IS - 2 UR - http://ijmcmed.org/article-1-1044-en.html SP - 30 EP - 40 K1 - Mesenchymal stem cells K1 - metabolic pathways K1 - metabolomics K1 - systems biology AB - Various mesenchymal stem cells as easily accessible and multipotent cells can share different essential signaling pathways related to their stemness ability. Understanding the mechanism of stemness ability can be useful for controlling the stem cells for regenerative medicine targets. In this context, OMICs studies can analyze the mechanism of different stem cells properties or stemness ability via a broad range of current high-throughput techniques. This field is fundamentally directed toward the analysis of whole genome (genomics), mRNAs (transcriptomics), proteins (proteomics) and metabolites (metabolomics) in biological samples. According to several studies, metabolomics is more effective than other OMICs ّfor various systems biology concerns. Metabolomics can elucidate the biological mechanisms of various mesenchymal stem cells function by measuring their metabolites such as their secretome components. Analyzing the metabolic alteration of mesenchymal stem cells can be useful to promote their regenerative medicine application. LA eng UL http://ijmcmed.org/article-1-1044-en.html M3 10.22088/IJMCM.BUMS.8.2.30 ER -