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Mesenchymal stem cells from umbilical cord tissue as potential therapeutics for cardiomyodegenerative diseases – a review
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Trixi Hollweck1   , Christian Hagl1 , Günther Eissner 2 |
1- Cardiac Surgery Department, Munich University Medical Center, Munich, Germany.
2- Cardiac Surgery Department, Munich University Medical Center, Munich, Germany. , Guenther.Eissner@med.uni-muenchen.de |
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Abstract: (13247 Views) |
| Heart failure is one of the leading causes of death worldwide. End stage disease often requires heart transplantation, which is hampered by donor organ shortage. Tissue engineering represents a promising alternative approach for cardiac repair. For the generation of artificial heart muscle tissue several cell types, scaffold materials and bioreactor designs are under investigation. In this review, the use of mesenchymal stem cells derived from human umbilical cord tissue (UCMSC) for cardiac tissue engineering will be discussed. |
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| Keywords: Umbilical cord tissue, mesenchymal stem cells, cardiac differentiation, non-degradable scaffolds, polytetrafluorethylene, titanium, bioreactor |
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Full-Text [PDF 231 kb]
(4442 Downloads)
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Type of Study: Review |
Subject:
Hematology
Received: 2012/04/25 | Accepted: 2013/09/14 | Published: 2013/09/14
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