[صفحه اصلی ]   [Archive]  
:: صفحه اصلي :: درباره نشريه :: آخرين شماره :: تمام شماره‌ها :: جستجو :: ثبت نام :: ارسال مقاله :: تماس با ما ::
:: جلد 8 - ::
برگشت به فهرست نسخه ها
Metabolomics and Cell Therapy in Diabetes Mellitus
:   (383 مشاهده)
Diabetes with a broad spectrum of complications has become a global epidemic metabolic disorder. Till now, several pharmaceutical and non-pharmaceutical therapeutic approaches were applied for its treatment. Cell-based therapies have become promising methods for diabetes treatment. Better understanding of diabetes pathogenesis and identification of its specific biomarkers along with evaluation of different treatments efficacy, can be possible by clarification of specific metabolic modifications during the diabetes progression. Subsequently, metabolomics technology can support this goal as an effective tool. The present review tried to show how metabolomics quantifications can be useful for diabetic monitoring before and after cell therapy. Cell therapy is an alternative approach to achieve diabetes treatments goals including insulin resistance amelioration, insulin independence reparation, and control of glycemia. OMICs approaches provide a comprehensive insight into the molecular mechanisms of cells features and functional mechanism of their genomics, transcriptomics, proteomics, and metabolomics profile which can be useful for their therapeutic application. As a modern technology for the detection and analysis of metabolites in biological samples, metabolomica can identify many of the metabolic and molecular pathways associated with diabetes and its following complications.
     
نوع مطالعه: Mini-review | موضوع مقاله: Biomarkers (diagnosis & treatment)
دریافت: ۱۳۹۷/۱۲/۲۲ | پذیرش: ۱۳۹۸/۲/۳۰ | انتشار: ۱۳۹۸/۲/۳۰
ارسال نظر درباره این مقاله
نام کاربری یا پست الکترونیک شما:

CAPTCHA


XML   English Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Larijani B, Goodarzi P, Payab M, Alavi-Moghadam S, Rahim F, Bana N, et al . Metabolomics and Cell Therapy in Diabetes Mellitus. Int J Mol Cell Med. 2019; 8 (S1)
URL: http://ijmcmed.org/article-1-1040-fa.html

Metabolomics and Cell Therapy in Diabetes Mellitus. مجله بین المللی سلولی و مولکولی. 1398; 8 (S1)

URL: http://ijmcmed.org/article-1-1040-fa.html



جلد 8 - برگشت به فهرست نسخه ها
International Journal of Molecular and Cellular Medicine (IJMCM) International Journal of Molecular and Cellular Medicine (IJMCM)
Persian site map - English site map - Created in 0.05 seconds with 32 queries by YEKTAWEB 3921