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:: Volume 2, Issue 4 (Int J Mol Cell Med 2013) ::
Int J Mol Cell Med 2013, 2(4): 169-176 Back to browse issues page
Antioxidant Activity and Glucose Diffusion Relationship of Traditional Medicinal Antihyperglycemic Plant Extracts
Fariba Asgharpour 1, Mehdi Pouramir *2, Asieh Khalilpour 1, Sobgol Asgharpour Alamdari 3, Mehrasa Rezaie 4
1- Paramedical Faculty, Babol University of Medical Scienes, Babol, Iran.
2- Cellular and Molecular Biology Research Center (CMBRC), Babol University of Medical Scienes, Babol, Iran. , pouramir@yahoo.com
3- Bureau of Education, Rasht-Region 2, Rasht, Iran.
4- Faculty of Veterinary Medicine University of Urmia, Urmia, Iran.
Abstract:   (10464 Views)
Plants with hypoglycemic properties are important in the treatment of diabetes. One of the mechanisms in reducing blood glucose is preventing the digestive absorption of glucose. The aim of this study was to evaluate the antioxidant properties of some traditional medicinal plants collected from different regions of Iran and their effects on glucose diffusion decrease. The amounts of phenolic compounds, total flavonoids, total polysaccharides, antioxidant activity and lipid peroxidation were determined respectively by folin ciocalteu, querceting, sulfuric acid, FRAP and thiobarbituric acid - reactive substanses (TBARS) in eleven confirmed traditional antihyperglycemic medicinal plants prepared at 50g/l concentrations using the boiling method. Phenolic compounds of Eucalyptus globules (100.8± 0.01 mg /g), total flavonoids content of Juglans regia (16.9± 0.01 mg /g) and total polysaccharide amount of Allium satirum (0.28± 0.05) were the highest. Significant relationship was observed between the polyphenols and flavonoids (p <0.05). The grape seed extract showed the highest antioxidant activity (133± 0.02 mg/g) together with decreased glucose diffusion as well as increased polyphenols (p <0.05), but the increase in antioxidant activity was not related to glucose diffusion. Antihyperglycemic plant extracts containing higher polyphenols showed more efficient in vitro glucose diffusion decrease, but no significant relationship was observed between antioxidant activity increase and glucose diffusion.
Keywords: Antihyperglycemic plants, glucose diffusion, antioxidant activity, polyphenols, flavonoids
Full-Text [PDF 93 kb]   (1237 Downloads)    
Type of Study: Original Article | Subject: Clinical Biochemistry
Received: 2013/06/16 | Accepted: 2013/11/24 | Published: 2013/11/24
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Asgharpour F, pouramir M, Khalilpour A, Asgharpour Alamdari S, Rezaie M. Antioxidant Activity and Glucose Diffusion Relationship of Traditional Medicinal Antihyperglycemic Plant Extracts. Int J Mol Cell Med. 2013; 2 (4) :169-176
URL: http://ijmcmed.org/article-1-86-en.html
Volume 2, Issue 4 (Int J Mol Cell Med 2013) Back to browse issues page
International Journal of Molecular and Cellular Medicine (IJMCM) International Journal of Molecular and Cellular Medicine (IJMCM)
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